diff --git a/arch/risc-v/src/mpfs/mpfs_usb.c b/arch/risc-v/src/mpfs/mpfs_usb.c
index c8b21b8b4b..2a6d871998 100644
--- a/arch/risc-v/src/mpfs/mpfs_usb.c
+++ b/arch/risc-v/src/mpfs/mpfs_usb.c
@@ -3430,6 +3430,10 @@ static int mpfs_usb_interrupt(int irq, void *context, void *arg)
   uint16_t pending_tx_ep;
   int i;
 
+#ifdef CONFIG_SMP
+  irqstate_t flags = enter_critical_section();
+#endif
+
   /* Get the device interrupts */
 
   isr = getreg8(MPFS_USB_IRQ);
@@ -3455,6 +3459,9 @@ static int mpfs_usb_interrupt(int irq, void *context, void *arg)
       priv->usbdev.dualspeed = 1;
 #endif
 
+#ifdef CONFIG_SMP
+      leave_critical_section(flags);
+#endif
       return OK;
     }
 
@@ -3539,6 +3546,9 @@ static int mpfs_usb_interrupt(int irq, void *context, void *arg)
       mpfs_resume(priv);
     }
 
+#ifdef CONFIG_SMP
+  leave_critical_section(flags);
+#endif
   return OK;
 }