diff --git a/arch/sim/src/sim/posix/sim_hostirq.c b/arch/sim/src/sim/posix/sim_hostirq.c
index ca38ab799a..bb1e92459d 100644
--- a/arch/sim/src/sim/posix/sim_hostirq.c
+++ b/arch/sim/src/sim/posix/sim_hostirq.c
@@ -87,6 +87,7 @@ uint64_t up_irq_flags(void)
  *
  ****************************************************************************/
 
+__attribute__((no_sanitize_address))
 uint64_t up_irq_save(void)
 {
   union sigset_u nmask;